• Dedicated transcript with three box C/D snoRNAs expressed from introns.

  • The spliced ncRNA (like CNAG_12489) is not conserved and probably without any predictable function, unlike the snoRNAs.

../../_images/tri_cnag12489_h99_igb.png

Three intronic box C/D snoRNAs derive from one transcript, pre-CNAG_12489





snoU2-30

  • snoU2-30_intronic-boxCDsnoRNA-141nt

  • Within 1st intron of dedicated transcript as unspliced CNAG_12489

  • Putative target D’-box in 25S rRNA: gggtTgggt; quite speculative; not seen in human or yeast; many sites in the genome of JEC21 fit grgttggrttgt, a longer, degenerate target sequence

  • Predicted target D-box in U2 snRNA: tcaTgtgta

  • Orthologue of human SCARNA9; the parallel position in human U2, an A, is modified by a small Cajal body-specific RNA, initially described as snoU2-30

../../_images/tri-I.png

>AE017344.1:303069-303210 Cryptococcus neoformans var. neoformans JEC21 chromosome 4 sequence
CGTTTGGATGAGCGTAACAATCCAACTCCTAAAGCCCTGTCGTCCCTCGAACCTCTTTAGTTAGGTTTGA
GTAAGAGGGCAGGACGTGCGCCGGGTAGGACCGGACAGCTGGAGGACCTTAATTACACATGACCTGAACTTC



snR41

  • snR41-intronic-boxCDsnoRNA-104nt

  • snoRNA in 2nd intron of dedicated transcript, like precursor of CNAG_12489

  • Predicted target for guide linked to D’-box: in 25S rRNA: atgAggtaaag; putative nucleotide that gets modified is 2 nt downstream of yeast snR49 target in 25S rRNA

  • Predicted target for guide linked to D-box: in 18S rRNA: caaGgctgaa

  • Orthologue of yeast snR41 (D-guide)

../../_images/snr41.png

>AE017344.1:303382-303477 Cryptococcus neoformans var. neoformans JEC21 chromosome 4 sequence
GCGCTATGAAGATAAACCACATACCATACATACTTTACCTCATTCGCCGGCGATTCGTCGTGATTAGCGT
GACACTTCAGCCTTGACTGAGCGCTC



snR70

  • snR70-intronic-boxCDsnoRNA-125nt

  • Within 3rd intron of dedicated transcript as pre-CNAG_12489

  • Predicted target in 18S rRNA: (tttgtaca)[c]ccgCccgtcg

  • Orthologue of yeast snR70

  • With accessory guide [van.Nues-2011] (its target is within round brackets)

../../_images/snr70.png

>AE017344.1:303637-303756 Cryptococcus neoformans var. neoformans JEC21 chromosome 4 sequence
TATTGTGATGAAAATCTTTCGATGGGCGGACAGATCCTAATCCCGTGCGCTCTGCGCTAAACACCTCGTG
TACAAAAGTAGGTGGGGAAAGGGAATTGGTGAATTCATCGTGATCTGAAT







  • Image source, including all exon sequences and intron sections:

# STOCKHOLM 1.0
#=GF RW van Nues, June 2023
#=GF https://coalispr.codeberg.page/paper
#=GS CNAG_12489/1-413 DE ncRNA spliced H99/1-1087
CNAG_12489/1-413                --------CTTTTTTCTTCTTCTCATTATCTACTCTGCAAGTTTCGTCTTCTCTCAAGCACCATGGCCACTTGAAT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATTAATCAATAAGATGAGGATCGCAGCTACTATGA-CAGATGTT---------------------CTTTCATGAT------------------------------------------AGGCTCTGG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CTGTAAAATCTCAAGCGCTTTAGTCATTTCTCT-TCCTGGTACCGCGCCAA-------------------------------------------------------------GTCACAC--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGACGAATCACTTTTGTGATCAGAGTAAGGTAAGCGTCATGT-CACATCCT-CGCCAATACCCCAGCGGGTTTGTCAACCTTGCGTGGCAGCGATATGGATATGAAGGTTCGTTCGTGCAACACGCTGTTCCGCGCTGGCAGCCAGACTAGGTCCTGTCAT-----TACATAG---CATTGTATCTCGTCAGTATGCGTTGTTCTGGAATGCATCTCTCGTTTTGTCATAATCGTG
Annot/1-150                     ----------------------------------------------------------------------------GTGnGT----------------------------------------------------------------------------RTGATGA-----------UGGGUUGGGCTGA----------------------------------------------------------------------------------------------------------------------------RTGATGA--------AUGUGUACU-CTGA--------------------------------------------------------------------------------------------------------------YAG------------------------------------------------------------------------------------------------------------------------------GtGnGt---------------------------------------------------------------------------------------------RTGATGA----------------------GAAAUGGAGUA-CTGA-----------------RTGATGA------------AAGUCGGAAC-CTGA-------------------------------------------------------------------------------------------------------------------------------------------------YAG------------------------------------------------------------------------------------------------------------------------GTGnGT------------------------------------------------------------------------RTGATGA----------GCUGCCCGCC-CTGA------------------------------------------------------ACAUGUUU----------------------RTGATGA--------------CTGA------------------------------------------------------------------------------------------------------YAG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS H99/1-1087 DE CP003824.1:c1535272-1536358 Cryptococcus neoformans var. grubii H99 chromosome 5, complete sequence
H99/1-1087                      ------------TTTCTTCTTCTCATTATCTACTCTGCAAGTTTCGTCTTCTCTCAAGCACCATGGCCACTTGAATGTGAGTTACATCTCTATTAATCT----------------------------------CCCCGCTTTCGCCTCCCTTTCCGTTCGGATGAGCGT---AACAATCCAACTCCTAAA----------------GACCTGTCGTC-C-CTCGAACCT-CTTAGTTAGGTTTGAGTAAGAGGGCAGGAC----------------------------GTGCGCCGGGTAGGACCGGAC-AGCTGGAGGACC-TTAATTACACATGACCTGAACTTCATTGACCACCTTCTTGTTGTGTGAT-----------------------AGACAGCTTGAAGAGTTGCATATGCTAACATTAGTGTTTTT----------------CAGATTAATCAATAAGATGAGGATCGCAGCTACTATGA-CAGATGTT---------------------CTTTCATGAT------------------------------------------AGGCTCTGGGTGAGTGG----------------------------------------------------TTTTTCCTAACCACCTTTCTCATGTTTCATGGGAGCGCTATGAAGATAAAA-CCACATACCATACATACTTTACCTCATTCGCCGGCGAT---TC---GTCGTGATTAGCGTGACAC---TTCAGCCTTGACTGAGCGCTCCTACTTTCCATACCTTCCTTTCTTACCTGTTAAGGTCATTGTAAT--------------GGAAGTGCTGACTGTAAG--------------------------------------------------------------TAGCTGTAAAATCTCAAGCGCTTTAGTCATTTCTCT-TCCTGGTACCGCGCCAA------------------------------------------------------------GTCACAC--GTAAGTTAT--AAACC----------------------------------------GGCTTTCCCTCTTCTTTCTACTGTGATGAAAA--TCTTTCGATGGGCGGACAGA--TCCTAA----------TCCCGTGCG-CTCTGCGC-----TAAACGCCTC--GTGTACAAA-AGT-AGGCGGGGAAAGG-GAATTGGTGA-ATTCATCGTG-ATCTGAATCTTCCATACATCTCTCTCGCCTTTTTCAAGCCCGCCCGCATTATTGTATGGTCA------------------GTTACTGACTACTG-----------TCGCAGGGACGAATCACTTTTGTGATCAGAGTAAGGTAAGCGTCATGT-CACATCCT-CGCCAATACCCCAGCGGGTTTGTCAACCTTGCGTGGCAGCGATATGGATATGAAGGTTCGTTCGTGCAACACGCTGTTCCGCGCTGGCAGCCAGACTAGGTCCTGTCAT-----TACATAG---CATTGTATCTCGTCAGTATGCGTTGTTCTGGAATGCATCTCTCGTTTTGTCAT-------
H99-expressed/1-356             ----------------------------------------------------------------------------------------------------------------------------------------------------------CGTTCGGATGAGCGT---AACAATCCAACTCCTAAA----------------GACCTGTCGTC-C-CTCGAACCT-CTTAGTTAGGTTTGAGTAAGAGGGCAGGAC----------------------------GTGCGCCGGGTAGGACCGGAC-AGCTGGAGGACC-TTAATTACACATGACCTGAACT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GCGCTATGAAGATAAAA-CCACATACCATACATACTTTACCTCATTCGCCGGCGAT---TC---GTCGTGATTAGCGTGACAC---TTCAGCCTTGACTGAGCGCTC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TACTGTGATGAAAA--TCTTTCGATGGGCGGACAGA--TCCTAA----------TCCCGTGCG-CTCTGCGC-----TAAACGCCTC--GTGTACAAA-AGT-AGGCGGGGAAAGG-GAATTGGTGA-ATTCATCGTG-ATCTGAAT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS JEC21-transcript/1-1097 DE transcript-with-3-boxCDsnoRNAs-1098nt AE017344.1:4:302950-304048:1
JEC21-transcript/1-1097         AACATCTCTATCACCTTTCTCCTTCTCATCTATCCTTCAAGTTTCGTCTTTTCTCAAATACCATGATTACTT-AATGTGGGTCACAT-TCTATTAATAT----------------------------------CCCCGCTTCTGCCTCCCTTCCCGTTTGGATGAGCGT---AACAATCCAACTCCTAAA----------------GCCCTGTCGTC-C-CTCGAACCTCTTTAGTTAGGTTTGAGTAAGAGGGCAGGAC----------------------------GTGCGCCGGGTAGGACCGGAC-AGCTGGAGGACC-TTAATTACACATGACCTGAACTTCATTGACCACCTTCTTGTTGTGTGAT-----------------------AGACAGCCTGAAGAGTTGCATGTGCTAACAATAGTGTTTTT----------------CAGATTACTCAATAAGATGAGGATCGCGGCTACTTCAA-CAGATGTT---------------------CTTTCTTGAT------------------------------------------AGGCTCTGGGTGAGTG-----------------------------------------------------TTTTTTCTTACCCTCTTTCTCATGTTCAATG-GAGCGCTATGAAGATA-AA-CCACATACCATACATACTTTACCTCATTCGCCGGCGAT---TC---GTCGTGATTAGCGTGACAC---TTCAGCCTTGACTGAGCGCTCCTACTTTCCACACCTTCCTTCCTTACCTGTTAGGATTATTATAAT--------------GGAAGTGCTGACTCTAAG--------------------------------------------------------------TAGCTGTAGAATCTCAAGCTCTTGAGTCATCCCTCT-TCATGGCACCGCGCCAA------------------------------------------------------------GTCACATGAGTAAGTTGTAAAAACC----------------------------------------GGCTTTGCCCCTTCTTTCTATTGTGATGAAAA--TCTTTCGATGGGCGGACAGA--TCCTAA----------TCCCGTGCG-CTCTGCGC-----TAAACACCTC--GTGTACAAA-AGT-AGGTGGGGAAAGG-GAATTGGTGA-ATTCATCGTG-ATCTGAATCTTCCATACATCTT----GCCTTCTCCAAGCCCGGGCGCATTATTGTATGGTCA------------------GTTGCTGACTGCTA-----------TCACAGAGACTAGTCACTT-TGTGATCAGAGTAAGGTAAGCGTCATGCCCACACCCTCCTCCAATATTCCAGCGGGTTTGTCAACCTAGCGTGGCAAC------GATATGAAGGTTCATCTGTGCAATGCGCTGTTTCGTGCTGGCAGCCAGGCTAGGT--TGTCATATCACTAGATAGCCTTCTTGTATCTCTTCAGTTTGCATTGTTCTGGAATGCATCACTCGTTTTATCATG------
#=GS snoU2-30/4-145 DE intronic-boxCDsnoRNA-141nt
snoU2-30/4-145                  ----------------------------------------------------------------------------------------------------------------------------------------------------------CGTTTGGATGAGCGT---AACAATCCAACTCCTAAA----------------GCCCTGTCGTC-C-CTCGAACCTCTTTAGTTAGGTTTGAGTAAGAGGGCAGGAC----------------------------GTGCGCCGGGTAGGACCGGAC-AGCTGGAGGACC-TTAATTACACATGACCTGAACTTC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS snR41/97-200 DE intronic-boxCDsnoRNA-104nt
snR41/97-200                    --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGCGCTATGAAGATA-AA-CCACATACCATACATACTTTACCTCATTCGCCGGCGAT---TC---GTCGTGATTAGCGTGACAC---TTCAGCCTTGACTGAGCGCTCCTACTTT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS snR70/1-125 DE intronic-boxCDsnoRNA-125nt
snR70/1-125                     ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TCTATTGTGATGAAAA--TCTTTCGATGGGCGGACAGA--TCCTAA----------TCCCGTGCG-CTCTGCGC-----TAAACACCTC--GTGTACAAA-AGT-AGGTGGGGAAAGG-GAATTGGTGA-ATTCATCGTG-ATCTGAATCTT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS R265/1-1073 DE CP025760.1:724305-725377 Cryptococcus gattii VGII R265 chromosome 2, complete sequence
R265/1-1073                     ------------------TTTCTTCTTCTCATCTTCACAAGTTTCTTTTTCTCTCAAGCACCATGATTACTTGACTGTGAGTTGCATTTGTCTTTAAT-------------------------------CTCTCTCCGCTTCGACTTCTCTTTCCGTTTGGATGAGCGT---AACAATCCAACTCCTAAA----------------GACCTGTCGTC-C-CTCGAACCT--CTAGTTAGGTTTGAGTAAGAAGGCAGGGC----------------------------GTGCGCCGGGTAGGACCGGAT-AGCTGGAGGACT-TTAATTACACATGAACTGAACTTCATTAACCACCTTCTTGTTGTGTGAT-----------------------AGGCAGCTTGAGGAGTTGCATATGCTAATAATGGTGTTTAT----------------CAGATTCATCAATAAGCTAAGGATCGCGGCTGTCTTTGGAAGATGT--------------------CTTTTTCATGAT------------------------------------------CGGCCCTGTGTGAGTGTG-----------------------------------------------------TTTCCTACCATCTTTCTCATGTCTCAATGGGAGCGCTATGAAGATAAAA-CCACATACCATACATACTTTACCTCATTCGCCGGCGAT---TC---GTCGTAATTAGCGTGACAC---TTCAGCCTTGACTGAGCGCTCCTATTTTCCC-ACCTTCCTTTCTTACATGTTAAGATCTTTGTAAT--------------GGAAGTGCTAACCCTAAG--------------------------------------------------------------AAGCTGTAGGATTTCAAGCTCTTCGAATCAACTCTCTGCCTAATACCGCGCCAAT-----------------------------------------------------------TCACACACCGTAAGTTAT--AAACC----------------------------------------GGCTTTGCATCTTCTTTCTATTGTGATGAAAA--TCTTTCGATGGGCGGACAGA--TCCTAA----------TCCCGTGCG-CTCCGCGC-----TAAACGCCTC--GTGTACAAA-AGT-AGGCGGGGAAAGG-GAAATGGTGA-ATTCATCGTG-ATCTGAATCTTCCATACATCTT----GCATTTCTCAACCCCGCCCGCATTCTTATATGATCA------------------TTTGCTGACTGCTG-----------TTGCAGGGATGAGTCACTTTGTGATCAAAT-TAAGGTAAGAGTCATGTTACACACTCCATTCATCATCACTGTGGGCTTGTCAGCCTAGCATGGCAGC------CATATAAAGGTTTAGATTTGCACTATTCCG-----GGCTGGCAGCCAGGTTTAGG-CTGTCTTGTCATTAGATTAGCACTCAGT--TTTTTCCGTATGCATTATTCTCGAATATATCGCTTGTTTT------------
#=GS WM276/1-1068 DE CP000289.1:767601-768668 Cryptococcus gattii WM276 chromosome D, complete sequence
WM276/1-1068                    -----------------TTTCATCTTCTCATCTTACACAAGTTTCTTCTTCTCTCAAGCACCATGATTACTTGATTGTGAGTTGCATTTATC---------------------------------TTTAATCTCTCCGCTTCGACTTCTCTTTCCGTTTGGATGAGCGT---AACAATCCAACTCCTAAA----------------GACCTGTCGTC-C-CTCGAACCT--TTAGTTAGGTTTGAGTAAGAAGGCAGGGC----------------------------GTGCGCCGGGTAGGACCGGAT-AGCTGGAGGACT-TTAATTACACATGAACTGAACTTCATTAGCCACCTTCTTGTTGTGTGAT-----------------------AGGCAGCTTGAGGAGTTGCATATGCTAATAATGGTGTTTTAT---------------CAGATTAATCAGTAAGATAAGGGTCGCGGCTGTCTTTGGAAGAT----------------------TTTTTTCATGAT------------------------------------------AGGCCCTGGGTGAGTTTG-----------------------------------------------------TTTTCTACCATTTTTCTCATGTCTC-ATGGGAGCGCTATGAAGATAAAA-CCACATACCATACATACTTTACCTCATTCGCCGGCGAT---TC---GTCGTAATTAGCGTGACAC---TTCAGCCTTGACTGAGCGCTCCTATTTTCCC-GCCTTCCTTTCTTACATGTTAAGATCTTTGTAA--------------TGGAAGTGCTAACCCCAAG--------------------------------------------------------------AAGCTGTAGGATT-CAAGCTCTTTGAGTCAACTCTCTGCCTAATACCGCGCCAGT-----------------------------------------------------------TCACACAGCGTAAGTTAT--AAACC----------------------------------------GGCTTTGCCTCTCTTTTCCATTGTGATGAAAA--TCTTTCGATGGGCGGACAGA--TCCTAA----------TCCCGTGCG-CTCTGCGC-----TAAACGCCTC--GTGTACAAA-AGT-AGGCGGGGAAAGG-GAATTGGTGA-ATTCATCGTG-ATCTGAATCTTCCATACATCTT----GCATTTTTCAACCCCGCCCGCATTGTTGTATGATCA------------------TTTGCTGACTGCTC-----------TTGCAGGGATGAGTCATTTTGTGATCAAAT-CAAGGTAAGAGTCATGTTACGCACTCCATCCATTGTCACTGCGGGTTTGTCAGCCTAGCATGACAGC------CATATAAAGGTTCAGATTTGCACTATTCCG-----GGCTGGCAGTCAGGT-TAGG-CTGTCTTGTCATTAGATTAGCACTCACT--TTCTTCCGTATGCATTATATTCGAATGTATCGCTTGTTTT------------
#=GS CryWin/1-867 DE AWGH01000011.1:c22510-21990 Cryptococcus wingfieldii CBS 7118 supercont1.11, whole genome shotgun sequence
CryWin/1-867                    -GGATCGGGTCTTGTGCATTTTCTTCTTCTTCTATGTTCTCCTTGCCCTCTTCAGCCTGCGCGTACAAGCCCTCTCGTGAGTCGTTTCTTCA-------------------------------------------GTCGTGTCTTGTCTCTGTCAGCTGGGATGA--------GCATTCATTGCCCTAAT------------------CTTGTC-CCCACTCAGAACCT--CTAGCAAGGTCTTGGGTG--AGGCAGG------------------------------TAGCCCCGG-CAGGACCGGGTT-GCTTGCGGACT--CAATTACACATGATCTGATTCGCACGCTCGAGATACCTTTCACTGGAT--------------------------------------GGACGTACGCTGACCTTACT----------------------CAGATGCAGTCGAAATTAGCATATACTTCATACGG---------------------------------TTTTCAAGACTTCT------------------------------------CTTTTCATAACGTGAGTA-----------------------------------------------------------CCCCTCTCAATTCACACTCTTCTATGGAACGCTATGAAGATAAAA-CA-CATATCATACATACTTTACCTCATTCGCTGGCGAT---AA---ATCGCGATTAGCGTGACA---TTTCAGCCTTGACTGAGCGTTCCATCCCTAGACCCGTTGATTTGT--GTAGTCAA---------------------------CGTGAGCTAACGCTTTTCGCTTGT-------------------------------------------------------TAGTTTCTTGATTGGACGCGACCTCGATTGCTTTGGATATGAATGGCGTCCGCCAACGCGTTTATGCCAA--------------------------------------------TTGCCCCTCGTAAGTACATTCTCCAGTCTGCCGAGTCAGG-----------------------------------GGCGTCATTTCTGTGATGAAACAA---TTCGATGGGCGGACAGA--TCCTGC----------TCCCTTGCG-CTCTGCGC-----TAAACGCCTC--GTGTACAAA-AGT-AGGCGGGGAAAGG-GCCATGGTGAT-TCCATCGTT-ATCTGATCTATGACCTTCAGTGATATCGTCTAGAC-------------------------------------------AAGATGCTGACCAATGGTTA----------TAGCTTGTCCCTTTGGCGAATCTTCAAGCTTTATGAGTATCGGCGACTCTGTGT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS CrySki/1-892 DE BCHT01000020.1:c99991-99100 Cryptococcus skinneri DNA, scaffold: scaffold_19, strain: JCM 9039, whole genome shotgun sequence
CrySki/1-892                    ----------------------------------------------------------------------------------------------------------------------------------ACCCAAATCCCCAATCCCCACCCAGTCTCTGATGACCAT---AACAATCCAACTCCTAAA----ATCATCTCTCCTCTCCC-GGCTCTCCTC-GAACCT--CTAGCCAGGTTTCTGTGATCCCGTGGTGGGAAGAGATGGT-----------------GTGCACCGGGTAGGACCGGAT-GGCTAGAGGACCTTAATTTACACATGACCTGATCCAACTTTCTCCTTCTTTTCACTTT--------------------------GGGGGAGCTTGATAGTTGAACGAGACTGATGGTTG-----------------------TAGTTAGGATCTTGATTAGGGCATAGTACCAGGTACTACAGCAGCTACGG----------------------AATGA------------------------------------------------TAGTGTGAGTATTTCTCGCCTTATCC--------------------------------------------TATATATTTCAACCTGCAAGAAATTCCCGCGCGATGACGATACAA-CA-TTTAC----CATACTTTACCTCATTCGACGATGAT---CTATGATCACGATTGGCGAGACAC-TTTTCAGCCTTGGCTGAGCGCTTTCCTACCCCTTCTATCTTGTTTCTA-------TAGTTCTGTACTATCCATATCGGAGATTAAATCACTGACATTAATCACTTGATTT----------------------------------------------------CAGATCGTCTATAATACCAAGCTGACAGGTCCATGAACGGCCTCGGCATACACAACAT--------------------------------------------------CTCACTGACGTATACGTAAGTTCCCTCCCTTTATACATACATCAAGAT--TCCACCCCTACCCAGATCATCCCCCTCCTACCCCACTCCTTCAATGAAGAAA---TCCCTCGATGGGCGGACATA-CCCCTCC-----------CCCAAGCG-TTCATCGC-----TAAACGTCTC--GTGTACAAA-AGT-AGGCGGGGGGAGT-GTACTGGTGATATCCATCG-ATTTCTGAGTCATGAGTCACCCACCCTTGTGCTCTTTCGTTGCTGGGAACAGCGTTTATTGGGGAAACAGAGAAACACAGCACGAGCTGACCAACCTTGTTTGCA-----TA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS VanPse/1-771 DE CP086717.1:728028-728798 Vanrija pseudolonga isolate DUCC4014 chromosome 4
VanPse/1-771                    ------------------------ACTGCAGCAGCGCACGCGCGTGACAGAGTCCACACCATGGCTCACTAACATTGTAAGTGTCTCCTCCTA---------------------------------CCCCCTCCACCCCTCCCCCCCGGCTCGAATGTTTGATGAGCACT---ACAATCCAACTCTTAA---------GCGCTGCGCCCCGGTGCGTGGTTGCGAACCT-CTTAGCAAGGTTCGTGGACGCGGGCTGGGGA-CAGCGC--------------------ATGCGCCGGGTAGGACCGGATCCGCTTGAGGACCACT--TTACACATGACCTGACGCTTGATGTCTCCTGTCTTTATTCTTTGCGAG-------------------------------TGTGGACGGGTAGCTGACAACGACCT--------------------TAGGACTATTGACTTGACTGACTAGACTCGATCCTCTGGGCGAAG----------------------------CTGGTATTGC-------------------------------------AGGCACAATGTAAGTCTCAGAA-----------------------------------------------------------CTCCCCTCCCCCCATCCTCCCTGCGCAGTGAAGATAAAA-CA-TATAC----CATACTTTACCTCATTCGTAACCCGCT--TC--GGCGGCGATTGACGAGACAC--TTTCAGCCTTGACTGAGCGCAAACACTCTCCCTTTCTTT--------------------------------ATGAAGAGAGACAAAAGCTGACGCTT----------------------------------------------------------------TAGCATTAGACGTCAACGAGA-GTGGACAACGGGCCACGATGGCGGCAACTCAC------------------------------------------------------------TCCCTACTGGTAAGTCTAGCCACCCCCTTCCCCCT----------------------------------------CCCCCTCTCTCCGTGATGAAA---TCTATCGATGGGCGGACAGCA-TCCAAA----------TCCCATGCGGCTTCGGCTGC---TAAACGTCCC--GTGTACAAA-AGT-GGACGGGGAAGAG-GACTTGGTGA--TTCATCGTT-TTCTGATCCTCCTACC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS VanFra/258-1026 DE BEDY01000004.1:c61222-60197 Vanrija fragicola DNA, scaffold: scaffold_4, strain: JCM 1530, whole genome shotgun sequence
#=GR VanFra/258-1026 SS         ------------------------------------------------------------------------.------------------...................................------------------------------......................................(((((((....((((((((((.....((((.((((........)))).))))....))))))))))...)))))))....................((.((((......))))....))................................-----------.-------------------....................................-----------------.......................-----------------------------------------------------.....................................................................------------------..............................................................---------------------..................................................................................................................---------------------............................--------------------------.........................................................--------------------------------------------......................................................................-------------------------------------...............................................-....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
VanFra/258-1026                 CACCTTGCTATGATTCCCATGCCTCGCATGCTTGGAGACGCTTTGAGCCACTCTCAAGTGCTTCCTTACTAA-CAGGTAAGTCTCCTCTCT-----------------------------------CCCCCCTCTGCTTTCTTTCCCACTCTCAATGCTTGATGAGCACT---ACAATCCAACTCTTAA-----GTGCTGT-CACCCCATCAAGT-CGA-GACGTACCT-CCTAGCTAGGT-TGTC-AAAGCTTGGTGGG-C-GCAGCAC------------------ACGCGCCGGGTAGGACCGGTACCGCTTGAGGACCAC--TTTACACATGACCTGACGCAACCATTCTTC-TCTCCTTTCTGTCGAGAGA------------------------------------GTACGAGCTGACAAGCA-----------------------TAGATTCTAACCTGCTTCAAAGCAACTCACGCGGAAAACAGCCTGCCGTGTGC---------------------------------------------------------------------CTCCTGAGTAAGTGTCAA--------------------------------------------------------------CCTCCTTTCCACTTCCCCCACGCGCTGTGAAGATA-AA-CA-TATAC----CATACTTTACCTCATTCGTAACCCGCT--TC--GGCGGCGATTGACGAGAAAC--TTTCAGCCTTGACTGAGCGCACACTTCATCCCACCACTCTTTGTGATAGT----------------------------GGACAAAACGCTGACCGCGAAAAGCC---------------------------------------------------------TAGACGATTCCATTGACCTCGCACCTCCTTTCCTCAAGACTTGT----------------------------------------------------------------------CTCCACCTGGTAAGCATCCTCCCAATCCCAGGCGCGC-----------------------------------------------ACTGTGATGAAAA--TCTTTCGATGGGCGGACAGTA-TCCAAAG---------CCTATCCAAGCTTCGGCTTGG--TAAACGTCCC-GGTGTACAAA-AGT-GGGCGGGGTGGAG-GAGTTGGTGA-ATTCATCGTG-ATCTGATCTT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS ApiMyc/1-1075 DE CP053621.1:c8652560-8651460 Apiotrichum mycotoxinovorans strain CICC 1454 chromosome 2
ApiMyc/1-1075                   ------------------CATCTACTTCCCCCTCAAGACGATGATCGCACACCGCCAACCGCAACCTGTTTACTGAGTAAGTGCTCTG-------------------------------------CCCCTCTCAGCTTTCGTCCCCATCTCTGCTTGATTGATGAGCACT---ACAATCCAACTCCTAA----------------GCGTCGTT-TTATCCTTCGAACCT--CTTGCCAGGTTTGTTGGATG-GGCGGCGC----------------------------ATGCGCCGGGTAGGACCGGGTCCGCTTGAGGACTA--TTTTACACATGACCTGACGCGTCTTTGTTTCCCATCTTGCTGCAGTTCTGTTT-------------------------------GTACAGCGAGCTGACCAACTC----------------------AAGCCTTTGTTTTGTACTGATCTCACTGCTCGGT---------------------------------CTTTTCAAGATCAGTGTGTCTTCCTT----------------------------CCTACTGAGTGAGTACTT------------------------------------------------------------------CCTCCCACGTCACCTTCTGCGCTATGAAGAAG-AA-CC-TATAC----CATACTTTACCTCATTCGTAACCGGC---TCT--GCCGCGATTGCCGAGACA---TTTCAGCCTTGACTGAGCGCTCAACTCCCACAAC-TCTTTCCCTGTC----------------------------GAAACACGTGTCACTGACCGCG----------------------------------------------------------------TAGCCACATCCTCCAGCTCCGAGCACCCACCAGCCTTCAAGTCGTGTACCATAGCTTTTC------------------------------------------------------GTTCCTAAGGTAAGCATCTTCCCCCCTTACATTCTG---------------------------------CACACCCAAAAGCACAACCGGATGAAA--TCTTTTCGATGGGCGGACAGTA-TCTAAA----------TCCTGCGGGCAACCGC--------AAACGCCCC-AGTGTACAAA-AGT-GGGCGGGGAGGAG-GACTTGGTGA-ATTCATCGTG-ATCTGATCATGTGTCTTTTGTGGC-TGCTGCTTGCTTCTTCCATCGGTGTGATGTTGAGCAAGAACA--------------TGGCTGACAGACAGCATCACAA--TAATAGTACCACGCTTTGTGTTGTTTCCATCGTTGTAGATCTTGTCTGTAATGAACATTTGTCCTCGCCGCTTTTGTGGCTCCACCATGGTGCCTTGTCCCCGTTGCTACATGCAGGATCCTTGCGATGAGAACGGAGGAAGGAAAGATTAATCAGCTGCTGATGAGCCCTTCTAAGGCGCCAATGATACACTGCAAGAGGCTCTGAGCCCATCGCGGTATCGAGAGACTACGCCTGCAA--
#=GS KwoHev/1-1136 DE ASQB01000005.1:434266-435401 Kwoniella heveanensis BCC8398 cont1.5, whole genome shotgun sequence
#=GR KwoHev/1-1136 SS           ...........................................................................................................................................................-...................................(((.((..((((.((.((.(.((((((.((((((((((........))))))))))........))))))......).)).)).))))..)).)))...((.((((......))))....))................................----------------------------------......................---------------------------------------............-----------------------------------------------------......-----------------------.........................................----------------------------------------------------------------------------------------------------..................................................................................................................----------------------------------------....---------------------------------------------------.....................................---------------------------------..............................................................................----------------------------------------------------------------------------------------....................................................................................................................................................-------------..--------------------------------------------.......--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....................................................
KwoHev/1-1136                   -----------------------------------------------------------------------------------------------------------------------------------------------------------TTCCGGATGACCAAT--AACAATCCAACTCCTAAA-GAC-TCTTGAGACTGCTTCT-TCTCGC-TCCCGAACCT--CTCGTTAGGTTTGGGA-CTCACA-GTGAGA-CTTA-GCAATCA-TCTCTTGATGTC-GTGCGCCGGGTAGGACCGGAT-AGCCAGAGGACTATCTTTTACACATGACCTGATCAATACATCAATCGCCTCGTCTTTCCCCTTATCAAA----------------------GTGGCTTGGCCAAAGAAGGTGACCGCTAACCTTGGTGTC------------TAGTGCTATTCCAGTAATCACGATGGATAGATGATTTCTTCATGTTTTGTATC------CTTTTCCGTGTTGGTTGATTGCT-----------------------------------------GTACTGGTAAGTCAATTCTTTGCCAATATACCAAGAATCGAGCCAAACCAGTATCAATGCCCCCTTCCCTCATCACCAACCTTCCAAACCCTAAACCCCCACGCAATGAAGATA-AA-CCT--TATAAC-CATACTTTACCTCATTCGCCGACG----ATCC--GTCGTGATTGGCGTGACA--TTTTCAGCCTTGACTGAGCGTTCATTCTCTACAACCTCTTTACCTCTTTTCGGCATATGACTCAACGAAA----GCGAGAGTGCGATTGCTGATTGTTGACTGTTACTTTACGTTGACATCGCAA-------------------------------------TAGACTGCTACTGTGTATCGAAGCGACTCACCA------------------------------------------------------------------------------TTTACTAACAAGGTAAGCTTCACCCTGTTCACTTCTACCCGACGCGAATCCACTTTACTTCCACTTTACTTGCCCCTTCTTTCCCCTCCTCTGATGATA---TTTTCCGATGGGCGGACAGA--CCCCCGA---------TCCTATGCG-CTTTGCGC-----TAAACGTCTC-AGTGTACAAAAAGT-AGACGGGGAAAGG-GAACAGGTGATATCCATCG-ATATCTGATCTTCGAAATTTTTCGTC--GCACATTCTGTGATCCAGACGTACAGCAACGGACACAAGAGTCT-------ATGATGGCTGACCGTGTTCGTGTCTGCTCTATAGATTTCGATTCCATTGCGAACTTCAAGCACCTGCTGGCTTGGCAGGACTAGACGGCTGTTTCGTTTGACGGTAGAAAATAGAGTAGTTTAGTTGAGAATATAACACACCGAGTACTTGTATCAGACACATTACTCCTTGCTTCAGCCCTCTAATAGATGCATCAGTCCTCTGTCCTTGCAATGCA----------------------------------------------------
#=GS KwoSha/1-1161 DE NQVO01000067.1:19277-20570 Kwoniella shandongensis strain CBS 12478 scaffold00067, whole genome shotgun sequence
KwoSha/1-1161                   ---------------------------------------------------------GTTGCGCTTTTATCGTATGGTGAGTCCCCTTACCATCTGACCCTCCGCTCGTCTGCGTGACCTCGTCACTCAGCACAGCACTCACCACCCTCTTCACATTCTGGATGACCATTTTAACAATCCAACTCCTAAA-------------GACTGTCGTTT-C-CCCTTTGAACCT-CTTTGTTAGGTTCGTAGGG-ATC-AAACGGCAGTC-----------------------GTGCGCCGGGTAGGACCGGA-CAGCTAGAGGACTTTCA-TTACACATGACCTGATACCTACCCTTCTCTCAAGGTCTCATTGTAACCACT-------------------------------GGAACCTAGACTGACTTTCTGCGGTTTCTCGTTGA--------CAGGTCTCGTTATGTATCTTATTCGTCGTTCTGTTCTGATTGCATCATGTCTT-------------TTACGTTCTGATT--------------------------------------------TTACTGGTGAGTTGCTCTTCTTGTCGCTCTCTCGCGTA-------------------------------------CCCACCCCCACCCCATCCCTACCGAACGCTGTGACGATACAA-CA---CATAAC-CATACTTTACCTCATTCGCCGACGAC--ATCG---TCGTGATTGGCGAGACA--TTTTCAGCCTTGACTGAGCGTTCAATCATCCCTCGCCTCAATTCTCTTCCATCGTAGCTTTGTAT-------------AGGGGTCCATGCTGACGCTCGGTCCTCGATA-----------------------------------------------------CAGACCTTGACGAGTA----------------------------------CTGACCTGATCTCAGAAGGCACATTGTG------------------------------------GCAGTTACTGTGAGTGTCCTCCCGTCGTATCTTTTCTTG-------CTTTTCCTCTCTATTCATTACCACCCATTATTCCACTCTCTGTGATGATA---CTTTCCGATGGGCGGACAGA--TCCTGC----------TCCTCAGCG--TTCGCGC-----TAAACGCCTC--GTGTACAAA-AGT-AGGCGGGGAAAGG-GAATTGGTGATATCCATCG-ATTTCTGACCTTTTTGTTGTTCTTCTCTACTTTGACCTTTGTCTCGATGTCCGTAAGAGCGC--------------------AAAGCTGACGGTGATGAACC-----TCCTAGAACCCATCCAGTTTGATCAATTCTACCTTCTTAGACTTTGCGTTCTGTCGTGTTGTTTTATAGCGTATTGTACATTATTTTATAGCGTATTGTACAGTATTTTATAGCGTATTGTACATTATTTTATGGATGTTTGTGATACATATCATTGAGCTTCAGCCTGTCCAGGCCCTCTGTTGTTGCGCATATGAGTGTACAGTACATGTAACAAGCACGTTGTCGAGACGATGTTCA--
#=GS KwoDej/1-937 DE ASCJ01000008.1:397340-398276 Kwoniella dejecticola CBS 10117 cont1.8, whole genome shotgun sequence
KwoDej/1-937                    --------------------------------------------------------------------------------------------------ATAGTCCTTCACAACTCTCCTCCACGATTCTGGCCCCTGTCGAGCGCATACTTCTCTTTCCGGATGACCAT---AACAATCCAACTCCTAAA-GACCTGTTCGA----TTTCCTTCTTCACCCTTGAACCT--CTCGTTAGGTTCATTGGTGGGCT-GGATACCCCTCG-TCAGGTC-------------GTGCGCCGGGTAGGACCGGAT-AGCCAGAGGACT-TCA-TTACACATGACCTGATATTTCAACCTCCCGCTCCATTGTCGGTCTCCTTTGGTT---------------------------GGAGAAGATTGCTGATT---------------------------CAGTTGAACGATAGACCACATGAATATGGCCTGATACACGACGGCGAAC--------------------CATACTGACGCTGTCCATATGGTCAATACGCTCCAATCCTCTTCAATGATGTCCTTACTAGTGAGTGTGATTTGTT---------------------CCCACCTCCGGCCCACTGTGCCTCTTTCCGCCCGACCGGAAAATAACCCCACAAAGAACGCGATGAAGATAAAA-CTTCTTAC----CATACTTTACCTCATTCGCCGACGAT---CC---GTCGTGATTGGCGAGACAA--TTTCAGCCTTGACTGAGCGTTCCCTCTTCTCCCTTCTCTCTCTTCCAATCTCTTTGGAATATAGAAGAC--GAAAGTGGAATGCCTTGCTGACGAAAATTCCACCTGT-----------------------------------------------------CAGACTTGCCTGTGCTGATCGGCTCCCT-------------------------------------------------------------------------------------------TACTGTGAGTGTCTACCCTCTTCCTCTTTCACTTCAAGAAG----------------------CCTCTTCTTTCACACCATCATGATGATAA----TTCCGATGGGCGGACAGAC-TGCCTGA---------TCCCATTCA-CTTCGGTGA----TAAACGTCTC-GGTGTACAAA-AGT-AGGCGGGGTGAAG-GAACAGTTGATATTCATCG-ATATCTGATCATTCTCCTCATCACGCCGCTCACTCGTGTCTTGTATATTTGTCAGGGCTC----------------------AATGCTGACCTGCGTGAA-------TGATAGGACGTGCTCAATCTTTTCTCTGAA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS KwoPin/1-895 DE ASCL01000030.1:280503-281397 Kwoniella pini CBS 10737 cont1.30, whole genome shotgun sequence
KwoPin/1-895                    -------------------------------------------------------------------------------------------------------------TGCTCTCCTCATTGTATTCCTCATTGTCCAATCCGCGCGCTCCTCATCTAGGATGACCAT---AACAATCCAACTCCTAAA-GACCTGTTCGA----TTTCCTTCTTTACCTTTGAACCT--CTTGTTAGGTTCATTGTTAAATTGGGATACTATTCG-TCAGGTT-------------GTGCGCCGGGTAGGACCGGAT-AGCCAGAGGACTT-CA-TTACACATGACCTGATATCAACCGATCAATCGCTCTTATGACTGTCGTTAAAT---------------------CCATGGCAGACGGAAAGGCTGATCAATTGGCATTTT---------------CAGATTCAATGAATTGTCTGTTTCTTCGAATCCT--------------------------------TATTTTACTGACCAAGCTTGCAAAACATCTAT-------------AAGCAAAAATATATACTAGTAAGTGCTTTTTGA--------------------------------------CTCGTTCTCGTATTCTATCAATTCTCAAACACCCCGTTTGAACGCGATGAAGATACAA-CATCTTAC----CATACTTTACCTCATTCGCCGACGAT---TCG---TCGTGATTGGCGAGACAA--TTTCAGCCTTGACTGAGCGTTCAACTATCATTCCCCATGTCTTACTACCGAGAAGAGGGGTCAT-----------------AATTGTGCTGACGATACATTGCTGTTCGT---------------------------------------------------TAGACCTACTTTTAACATAAATACCGATTCT-------------------------------------------------------------------------------GGAATAGCTTACTGTAAGTTCACCTCCTGTTGG------------------------------AAAAATCTTCTGAATCACTTCCACCATTATGATGATAA----TTCCGATGGGCGGACAGAC-TGCCTGA---------TCTCATTCA-CTTCGGTGA----TAAACGTCTC-GGTGTACAAAAAGT-AGACGGGGTGAAG-GAACAGTTGATATTCATCG-ATTTCTGATCATACTCCAAATTCTCATGTTCAGCTTTTTATTTCCGAAAA----------------------------GATAGATGCTGACATCTGATGTTGA-------TAGGATGTTCTTTCTGCGTGCTGCTTGGGTGGT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS PapLau/1-920 DE JDSR01000449.1:22362-23572 Papiliotrema laurentii RY1 contig_466, whole genome shotgun sequence
PapLau/1-920                    --------------------------------------------------------------------------------------------------------------------------------------------------ACCCGGTCTTCGCGGATGACCATT---ACAATCCAACTCCTAAT---------------TGCCTTGTCTC-CCTCTCGAACCT--CTCGTTAGGTTTGAGTCGTGAGTCAAGGTA--------------------------TCTGCGCCGGGTAGGACCGGGT-CGCTAGAGGACTT-CAATTACACATGACCTGATCCGACCGGTTCTCAACACGCCTTCGCCCGTAGAA-------------------------------------TGGCGCTGACCTCCAGTTGTTCCG--------------TAGTTTTTGCCTACAGGAGTACAAGTC-----------------------------------------------------------------------------------------------TCACCCAGTAAGTGTACTCTCCCGGTCAAAT------------------------------------------CCTTCCGCCTCCTCCCTTTCCCTTCCTAGCGCGACGACGATAAA--CCAATTAC----CATACTTTACCTCATTCGCCGACGAT-CAAAGA-ATCGCAATTGGCGAGACACC-TTTCAGCCTTGGCTGAGCGCTACTTCTTCCTCCGCTTTGCTCAATCGCAACCGAAGAG-----------------------CTCTGTGCTGATAT------------------------------------------------------------------CAGGGCTGGATTG----------------------------------------------------------------------------TTCCTCCTTGGATCGTTTTGACCCGTTCCTCCATGTAAGTCGCTCATT--------------------------------------------------CCTATTACACCTTTATGAAGAAAA---TTTTCGATGGGCGGACAGA--CCCCCCGA--------CCTCTCATTCCTTCGGGAATG--TAAACGCCTC-AGTGTACAAAAAGT-AGGCGGGGAAGGG-GAGATGGTGATTGTCATCG-GTTTCGGATCTTGCTTTGAGTTGAAAAGTGGTTTCAAGATTGG----------------------------------------ATGCTGATCC----------------ACAGATGTTTATTGCTACGTATTGTTCATTCTCTACTGTATAGATACACTTGCCCATGCATGTTGCTTTCTTGTTGCTTGACTTTGTACACCATCCGTGGCTTCTCATGCTCGTTTTATGGATCCACGTAGAGACGCTTGTAAAGGACGCCTGACGTTTTGACTCGGTTTCACCCGAAACATTCGGTTAACGATTTCTGAAAGTCGGTTGACATTCCGCAACACCTCTGGTCCATATA--
#=GS KocImp/152-1101 DE NBSH01000014.1:401238-402430 Kockovaella imperatae strain NRRL Y-17943 BD324scaffold_14, whole genome shotgun sequence
KocImp/152-1101                 TCTCTCTCGTGGGGAGCGACATCTTGACGCTGAGGGTACAATCATACACGCCCTGGGAGCGACCTCAGTGGAACCAGTGAGTCCTT-----------------------------------------------------CCGAGTGGATGACCGCGACTTGATGATCT-----ACAATCCAACGCCTAAT--------------------------TCTCGCCATACCT--CTCGTAAGGTTTG-CTTGA------------------------------------CTTGCACCTGGGTAGGACCAGG-ATGCTTGCGGACC-TCA--TACACATGACCTGATCGCATTATGTCGTCCAACATGGAAGT----------------------------------------------CTCGCTGATTCGTTA----------------------CAGGTGGACAATTGGTAGCTCGCCATTCTATACCG------------------------------------------------------------------------------------------TTATGTGAGTACCTCTTTCCTCCTGCTCCTCCCGCCCTCCGA-------------------------------------------TCTATCTCTTCCATTGCTATGACGATAAAA-CATCTTAC----CATACTTTACCTCATTCGCCGGCGGT--CTCGA-ACCGTGATTGGCGACTCAAA-TTTCAGCCTTGACTGAGCGACTATTTCTCTGCATATCCTCACTGTACCACGAAT------------------------------CGCGCTGATCCCACGA-------------------------------------------------------------CAGGTGTC----------------------------------------------------------------------------------------------------------------CCTGTAAGTCACAGCTCGAC--------------------------------------CCCCTCCCCTCCCCTCCCCATTCATGACGAAAA--CTTTACGATAGGCGGTCATA----------------CTTCCCTCCTCCTCTGGTTCGTCC-AGAACGTCTCCAGTGTACAAA-AGTGAGACGGGGAGGAGTGAC-TGGTGAAATCTATCG-ATATCGGATTATCAGCCATGCACTCCAGGGATAGTGATCT------------------------------------------CGAGCTGACCCCTGCCAC----------CAGGTTGGATGTATGTATCTCTATGTATGCCAAATGAAATATATTCCGCTGTCCATTTTCTCCCATTTTCTCCCGTCCAATGACAGGAATTCATACCGACTCAACTTTTTTTCCTTATCGCTTCTCTTTCTCTCTCTCTCATATCTCACTCAACCAACTCAACAGCTCGTCCGGCTGCTACCCTGCTCCCTTGACCGCTCCTCGGGCACTCTTATGTGGACCGAACGTACCTCTGAC--
#=GS TreFuc/1-1098 DE LBGW01000067.1:c1098-1 Tremella fuciformis strain tr26 contig67, whole genome shotgun sequence
TreFuc/1-1098                   ---------------------------------------------AACCCGCAACGCGACGGCGTGAATCGCAAAGGTGCGTCATTTTCATCCGGCTGCTACATCGAGCCTCCCTCTCG---------CCCTTCCTTCACCTTCGTCCGCTTGCCAACTTGATGAACAT---AACAATCCAACTCCTAAA-------------GACCGT-CA-GGTCGAGC-CAAGCCT---CATC-AGGTTTGAGCTTGGCC-C-GCGGTC--------------------------GTGCGCCGGGTAGGACCGGA-CAGCCAGAGGACCCA-TTTTACACATGACCTGATACCAACACCACCGCACAACGCTAC---------------------------------GACAATCTGGAGCAACTAGCTGATGCTAT-----------------------TAGTCATCGCACGCAGAATACGATAGGCCTGTCAAACGAGATGCT---------------------------CTTGACAAGAG------------------------------------------TCATGTGAGTTCCGTCTGCCTGTAT-------------------------------------CCAGCCCCTAATCTACATTCTCATCCTCCCTCCAACGCGCTGTGACGATAAAA-CCATATAC----CATACTTTACCTCATTCGTCGGCGGT---CAT--ACCGTGATTGACGAGACATC--TTCAGCCTTGACTGAGCGCTCGCCTCCTGGTCACCATTACGAATACGTTAGGGC----------------------------TCGTGCTGATCGTTCAAGCGCGACTGTCGATAGGTGCCGAAACTCATGATCGACTGCAATGATCTCGACA--------CAGGCTTGCTCTGAAGCAGAACATCGCCGGACCGTCAGCGAAGGCTTGATCGGGAAGCGACCGGAGCCTGCATGGA-------------------CATTCGCCAGGGCAGCAAACGAGTCCAAGTGAGTGCTGTTCCATCGCTGTGTTGGCTCCTTCGGGTGCAG-----------------CTCCTCCCTCGTCCTCCTTCTGATGAAAACCTTTACCGATGGGCGGTCATA--CCTTT----------GTCCTCTGTGCTATCGCGC-----TAAACGCCTT-TGTGTACAAAAGATAAGGCGGGGATGAG-GTCTTGGTGATATCCATCGATTCACTGATCTTTCGTTTATCTGCTCGACTTCGTCTCAGCGCGCGATGATTGCGAGACG-----------------------TTGGCTGACTG----------------CCAGTTGCAATACTTGGCTGTTGTCCTTGCGTCTGAGAGTACGGCCCGGCGTGTGCTGGTCATGCATGCTTTGTAGCGTCGACCCCAATGGACCTTCCCTCTTCAGGATGCATTGTTGTATGTTACTCGTGATCACGTGCCCTTC-----------------------------------------------------------------------------------------------
#=GS TreYok/1-949 DE BRDC01000025.1:c723024-722076 Tremella yokohamensis NBRC 100148 DNA, KCNB35TY.25, whole genome shotgun sequence
TreYok/1-949                    ----------------------------------------------------------------------------------------------------------------------------------CACCCACGCCTCAACCCCCTCTCCCAACTTGATGAACAT---AACAATCCAACTCCTAAA-------------GACCGCTT-GGACTGGGC-CAAGCCT---TACC-AGGTTTGAGCCTGG-CC-GGCGGTC--------------------------GTGCGCCGGGTAGGACCGGA-CAGCCAGAGGACCA-TTTTTACACATGACCTGACTTCGTTACACCCTTTACAATAGCGCAGGATACC----------------------------------GAGCAGACGCTGATCACAGATGTCATTCTTTGCGTCATGGAATAGTCTGCCCAAAAGCGATACAGATCCTACTGGCGATTGCAGAGGATCAAA-------------------------------------------------------------------------GCCGTGTGAGTCCATCATGCCTGCTCCTGCTCC-------------------------GTGCATGTTGCCATCTCACTTCCACTCAAACCCATATCAGCGCGCTGTGACGATAAAAACCACATAC----CATACTTTACCTCATTCGTCGGCGGT---TCC--ACCGCGATTGACGAGATA--TTTTCAGCCTTGACTGAGCGCTCAACCTCTGGCCAGAATTATATGAAATGCTACGAA--------------------------CATGAGCTGATCGCATAAGAATGACTCATTTCGATTCGTTGTCGAGTCCGCTCCGCATGACGGACCGATACGATTGCAACAGGCTGGCCGCTTTGAGGACGAATAGCATACTCGATCTTCGGGAAACGCTTGCTTGAAAGGCGGTCGAATGCTAT-ATGAGGCGTCAT-----------GCAAGGGCAGAG-------CCAAGTGAGTTCTGCTTTGCTGCTGTGCCCGCCTCTTT----------------AAACCCTCCTTACACCCACTCTCTCACCCTGATGAAAACCTTT-CCGATGGGCGGTCATA--CCTTT----------GTCCTATGTGCT-TCGGCAC----TAAACGTCTT-TGTGTACAAA-AATAAGGCGGGGATGAA-GTCCTGGTGATATCCATCGATACACTGATCCTTTGCGCACCTGCTTTGCTCCTCTCTCAGCGATGAACGTAGGAGCT--------------------------CGGCTGACTGC----------------TAGATGCCATGGACACAGACAACCCTCGTGTCT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS SaiPod/1-1115 DE RSCD01000023.1:c428614-427464 Saitozyma podzolica strain DSM 27192 scaffold_23, whole genome shotgun sequence
SaiPod/1-1115                   ---------------------------------------------------------------------------------------------------------------------GCGACGTCGAGCGCGCAATCAGTTCCTTCTCACCTATCAATTTGATGAACAT---AACAATCCAACTCCTAAC--------------GCCTCGACC-CTGCTCGTCGAACCT-CTTTGCTAGGATCGGCGGGCAGAGGTCGGGGC------------------------ATCTGCGCCGGGTAGGACCGGG-CCGCTAGAGGACCTTCA--TACACATGACCTGATCTCGTCGACACGTTTCGCCGTGGTTACTTTGGCTT-----------------GAGGTCGGCGAAGTGAAGTCTGAGCTGATCA--------------------------TAGCAGATGTATATCGTTGCCTTGGCCTGATACGTCCGAGTGGCTCGAGGTGTCGACTG-----------CTAATGACTGAGCTGCGGACGGTTGCA-------------------TCGGATTGTACTGGTGAGTCAGACTGCAAT-----------------------------------------CCATCTCATCTCTCCGCATTTCGTTACTACCCCCGAACGCGGTGACGATACAA-CTACA-AC----CATACTTTACCTCATTCGCTGGTAGC---TCT--GCTGCGGTTAGCGAGACATCTTTTCAGCCTTGACTGAGCGTTCATTGAAATCCCTTTCGCATTGTCTTACATGCGCAATGTACCGCGTTGCT------------GGATGCTGACACTGGTTCGCACCT------------------------------------------------------CAGACAGACCGGCAAGTGCCTCCGTTCCACACCGCATACGGAT-----------------------------------------------------------------------CGCATCCTGGTAAGCCTTGTTACCCTCTCCTTCTGAA--------------------------CCCCACACAACCCTTTCCTCTTTCCTGATGAAAAAC---TTCGATGGGCGGACTTAT-TCCCTCCTCTCTGGGCATCGCGCCCTCGGGCAGGTGTCCTAAACGCCTC-AGTGTACAAAAAGT-AGGCGGGGGGAGG-GAGCTGGTGATATCCATCGT-TTCCTGAACACGTTCGCGCTTTTCCCAGTTGTCGGTGGTGATGCGACTCGTCCTGGCTGGC---------------------TGGCTGACGCGATGTTC-------TTATAGGTTGTGCTGCTAGCGATCTTGCCCCATGGCCAAGCAATACGACTGACACCCAATGAGGCTGACATTCGTCCTCGATCGCATTTGTTCACCATTGTCCTCATTCACAGCTGTTCTAGTCCGATGTACCTAGCGTTGTGCCATGTATCACTTCACCTATGCATCGTGATGAGCAATCACGCCCGCAGCAATGTCACGGCCTGCCTGCCCAGGTGTTGTGCTTGCAATCGGTCGCCA--
#=GS TakKor/1-889 DE BCKT01000013.1:739106-739994 Takashimella koratensis DNA, scaffold: scaffold_12, strain: JCM 12878, whole genome shotgun sequence
TakKor/1-889                    ----------------------------------------TGCAATCTGCTTGCAATCTGCTTGCAATCTGCTTCAGCAAGTCTCGCT-----------------------------------------CGCTTTCACCTTCCCTCTCCCTCTGTTTTCTGATGAACGTT---ACAATCCAACTCCTAAT---------TTACTGTTGGA-ATGGTGGGT--CAAACCT--CTTGCTAGGTTTGCA-ACCT-CCATCTCCT-CAGTGA-------------------CACGCGCCGGGTAGGACCGGAATCGCTTGAGGACTA-TTTTTACACATGACCTGATCCTCATTTTCTGTCCCTTGACCGTGGTGAACTTGTTGTGGAAGAGAGTTATCCGGTGCAATGTTAGCTTACAGACACTGACGCTCTCCTTTA-----------------CAGACTCATTCACAGC------------------------------------------------------TAACTGACAATGCCGACCGTCTCTGACTGGCA-----------------------CAATGTGAGTATCGTGCTGCTCTCCCTTCATGATCATT------------------------------------------CCCTCCTGTCCCTTCCACGCGCTGTGACGATACAA-CTACA-ACCATACA-ACTTTACCTCATTCGTCGACGGC---TAT--GCCGCGATTGACGATACA--TTTTCAGCCTTGACTGAGCGCTCCATTCCTTTCTTCGGCTCTTGAGATTGCAAAGATGATCAGCA-------------------CCATGCTGACTTGTTTGCTC----------------------------------------------------------CAGACTGACCATTATTGCTACCACGACATCTCACTC-------------------------------------------------------------------------GCTGATTAAGTAGCGTGAGTCATCTTCGTCCATTCTCCCCTTTCTCATTCCCA-----------------------------------CTTTGTGATGAAA--TATATTCGATGGGCGGACATA--TCGCCCTCCTCTGTCTGGTGACCTCGGTCATCAGGC---TAAACGTCTC--GTGTACAAA-AGT-AGGCGGGGAGGTGTGAACTGGTGATATTCATCG-ATCTCTGAAATGGATCATTCTTCTTGTGGCTTGTTGTTCAGCACGATCCGTGATGA-------------------------CCATGCTGACGTCTTGAGCCAGC---TACTAGACGGTATTCAGTC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS TakTep/1-895 DE BCKS01000007.1:c991758-990864 Takashimella tepidaria DNA, scaffold: scaffold_6, strain: JCM 11965, whole genome shotgun sequence
TakTep/1-895                    -------------------------------------------------------------------------------------------TCTCTGGATCTAGTTGTATCTCCTGCACCTGAATACCATACAGCCATCCCCTCTTCCTTGCACTCTCTTGATGAGCAT---CACAATCCAACTCCTAAC-----------TCACTCGGGACGCAAAAGGTCAGAACCT--CTGGTTAGGTTTCCATCCTTGAGC-TCTC-AGTGG---------------------ACAGCGCCGGGTAGGACCGGAGTCGCTTGAGGACTTTATCATACACATGAACTGATCTTTCTTCTGCACTTTTGGAACAGATCATTTGGAATGGTTCAATCATCA----TTTTCGTTTTGCTAACAACCCTTCTAGGCA--------------------------TAGCTTGTCGGATCTTCAAAGCCATTCTTTTACTACTAACCAA----------------------------------------------------------------------------------CAATGTAAGTCATCTTACACATCCCATGTTCTCTCTCC----------------------------------------------ACATCCCATCTATCGCGCAGTGACGATAAAAACTATATACCATACAAACTTTACCTCATTCGTCGACGGT---TCT--ACCGCGATTGGCGAAACA--TTTTCAGCCTTGACTGAGCGCTCAAATTCCTCCCCCCATTCGTCCATGTCTTTTTTAGCATGGCGT-------------------CATGCTGACTTGGTTTCTTTC--------------------------------------------------------CAGACTGACTGACTTGTTCAACTTGAAATCTCACTGTACTGA-----------------------------------------------------------------------------CTGGGTGAGTAACTTTGTTTCATTTTTTATTTCTGGTTTTTCTTCCCCCTCCTCCCTTCAATCAACT-----------CTTTGTGATGAAA---TTTTTCGATGGGCGGACATCA-TCTCACTCCTTTGTCTGGTGATCTTGGTCATCAGAC---TAAACGTCTC-GGTGTACAAA-AGT-AGGCGGGGAGGTGTGAACTGGTGATATTCATCG-ACCTCTGACTCAACTGTCAATCCACATGGCAAAATCATGTCAA-------------------------------------GCCCGGCTGACGATTGAAG-----------CAGACTGCTACGTCGTTGTGACAAAACATCCTTTTTTTTTTGGCTAT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS CutMuc/54-782 DE BCJT01000005.1:534174-534955 Cutaneotrichosporon mucoides DNA, scaffold: scaffold_4, strain: JCM 9939, whole genome shotgun sequence
CutMuc/54-782                   ATCCTCTCAACGCGCATGTTTTTGTGACATCCCCTAAGCCTGGCGTGGCCATGTTCAAGCCTCTAGCCTTCTGACAGTGAGTGAGT-----------------------------------------------------CTCCCCTCCCCCATTCTGCTTGATGAACATT---ACAATCCAACTCCTAA-------------------GCGCGTCGTTGCC-CGAACCT--CTTGCTAGGATCGTGGTG-CGGCGCGC-------------------------------GGCGCCGGGTAGGACCGG-TCTGCTTGCGGACT--ACATTACACATGACCTGACGCCTTTTCTCCCTTCTCTTCTTCCTGCATGAGCAG------------------------CGCTGACAGAGTAGCTTCTGATGA--------------------------CAGCTGACCCCTCTCCCGGCTCGAGCTTCTT--------------------------------------CCAACTGA----------------------------------------------------GTGAGTGCATCTT----------------------------------------------------------CCCTCCCCTTCCCCCCTTATCCCGCGCTGTGACGA-ACAA-CC-TATAC----CATACTTTACCTCATTCGTAACCGGC---TCT--GCCGCGATTGACGAGACA--TTTTCAGCCTTGACTGAGCGCTTCCCTCCAGCTTCTCTTTGAT--------------------------------------GAACAAAGCTGACAACCAGCCA-----------------------------------------------------------CAGATCTTCTCTCCAACCCATCCTGTACATACTCTCTCTCTG---------------------------------------------------------------------------CAACTGGTAAGTCTTCCTCGGCG---------------------------------------------------CAAACACACACGGATGAAAA---CTTTCGATGGGCGGACAGAAATCCAA-----------GTCCCTTGCGCTTGCGC------TAAACGCCTCC-ATGTACAAC--GA-AGGCGGGGAGGAG-GAGTTGGTGA--TTCATCG-ATTTCTGATCATGTGTTTTGGTGTTGTCAGAATG------------------------------------------------TCCGCTGACAGG----------------CAGA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS CutCut/1-720 DE JAMALK010000093.1:c8356-7637 Cutaneotrichosporon cutaneum strain P1411 ctg_93, whole genome shotgun sequence
CutCut/1-720                    -----------TCCCAACGCGCTTGTTTTCCACCATGCCTTGACTTTTCTTCCTCACATCCAGATCCTCGTTCACTGTGAGTACC----------------------------------------------------------ACCTACCCCTCCTGCTTGATGAACATT---ACAATCCAACTCCTAA----------------------------GCGGCGGAACCT--CTCG--AGGTTA-GCCGC----------------------------------------GGCTCCGGGTAGGACCGG-TCTGCGTGCGGAC---ACTCTACACATGACCTGACTCCCTCCCTTCTCTTCTGTCGCGAGCAAAGCTAACGACA----------------GGTGCTAATCAACCGACTTGACTGACACCGGCGGCCTCC---------------AAGA-----------------------------------------------------------------CCAACTGA----------------------------------------------------GTGAGTTTGACGC-------------------------------------------------------------------------------GTGCGCTGTGACGA-ACAA--CACATAC----CATACTTTACCTCATTCGTAACCGGC---TCT--GCCGCGATTGACGAGACA--TTTTCAGCCTTGACTGAGCGCACCCTCAACCTACATGCTTCA-----------------------------------------TTGTAGCTGACAGA-----------------------------------------------------------------CAGCGACAGCTCCGCTGTCAAACCGCGACTCTTCTGCCGGGATTGTTCTATCTGAG--------------------------------------------------------------AAGTGGTGAGTCCATC---------------------------------------------------------CCCACACACTCGGATGAAAA---CTTTCGATGGGCGGACAGAAATCCAA-----------GTCCTGCG--CTTGC--------GCAACGCCCC-ACTGTACAAA-CCG-GGGCGGGGAGGCG-GAGTTGGTGA--TTCATCGT-TTTCTGATCTCAATTCCTGCGCACATCGCGTGGA----------------------------------------------TGACGCTGACCG-----------------CAGGTGGTGACGATGTCTATGTTGTGACACCGAGGGTGGACATCCAGCTCTAAAGGCTCGGTGT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS NaeEnc/1-821 DE MCFC01000036.1:c110325-109505 Naematelia encephala strain 68-887.2 BCR39scaffold_36, whole genome shotgun sequence
NaeEnc/1-821                    ---------------TCTGCATGCCCTCCCCTATTATATTTTTGCGCAGGTTCGAACCAAGCTGACAATATGATTGGTAAGTA--------------------------------------------CTCTTCTTTTCTTCCACCTTGACACCCGTTCCGGATGAGCATT---ACAATCCAACTCCTAAT---------------GCTCTCACC-TGGC-C-TGAACCT--CTTGTTAGGATCAAAGCCACGGTGTGGGC---------------------------ATTGCGCCGGGTAGGACCGGG-TCGCTTGAGGACT--ACTTTACACATGACCTGATCACCATTTATTCTCTCGAAAGATGTCATATATCCGCCT------------------------------AATACGAGCTGACCTGCTTGACAGAC---------------CAGACCTAC---------------------------------------------------------------TCTGACGTCCAAGTGTAAAGTCATTCCGATGTTGATG-------ACCTTTTCTTGCTGTGAGTACCGCTCTACCTCT---------------------------------------------------------CCCGTCATTTATCCTGGACGCTGTGACGATAAAACATACATAC----CATACTTTACCTCATTCGCCGGTAGC---TTAT-GCTGCGATTGGCGTGACA---TTTCAGCCTTGACTGAGCGTTCACTTTCCCCTTCAATGTTCCGCGATGACATCTTT---------------------------CAGAGCTGATGCGCTG--------------------------------------------------------------TAGGACAATGCGACGGTCTCACTAATCATT------------------------------------------------------------------------------------------TTGGTGAGCGTCTACCCTTTTTTTTCGCA---------------------------------CAACATACGGTCTCTTCTTGTGATGAAA---TCTTTCGATGGGCGGACATA--CCCCTTC---------TCCTATCC---------------CAAACGCCTC--GTGTACAAA-AGT-GGGCGGGGGGAAA-GACATGGTGATCGTCATCGG-TTTCTGAAATCAGGCTCTGCTCTTCATCAATGACATGTTGGCGAATGCTAACGAGGGCG----------------------TCAGTTGATGTTGCGTTTG---------TAGATACATTTGCGATGGAGCCCAGTTTT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GS PasPL2/1-827 DE JAMFRE010000028.1:c245950-245124 Pascua sp. PL2904B ctg_28, whole genome shotgun sequence
PasPL2/1-827                    ------------------TACGCGCTTGATTTCCACAAACTGCACTGCAACCAGCACCAGCAATGAGACACTGACAGTAAGTCGCCCT------------------------------------------TCTCCCTCATCCCCCCTCTTATCCTTGTTTGATGAGCATT---ACAATCCAACTCCTAAA--------------GCTCTGGTCGTCGGCGTGTGAACC----ACTA--GGTTC-CGCGTCGACGGTCAGTGCG-------------------------TGCCCCCGGGTAGGACCGGGATGGCTAGACGACCT-TTTTTACACATGACCTGACACCACTGCACTATCGCGCTCATCTCTTGTTTTCGGCAACGTGTAA-------------------------CAGGCGCTGACAGA-------------------------CAGGCTTCTTACCATGTATCAATCGCTCGCACACGCCCCGTATCCTAA--------------------------------------------------------------------------CTTCTAAGTGAGTATCTGTTTTCATC------------------------------------------------------------------CTGTCCAAAGCGCTATGACGATAAAA--CATATAC----CATACTTTACCTCATTCGTAACCGGC---TCT--GCCGCGATTGACGAGAAAC--TTTCAGCCTTGACTGAGCGCTACCAATCTTTTCATTTGCTTTGCAAAGGAA-------------------------------TCAACGCTGACAGCG----------------------------------------------------------------TAGCCAAACACAGAGCCAGAAGGCACCAGAACCATCCATCCAAACCACCACACCGTGC-----------------------------------------------------------TCCATCGTAAGTCTCAACCCATTTCCC-------------------------------------------------TCTTTTCTATGATGAAA-TAATATTCGATGGGCGGACAGTA-TCCAAGTCCCATGCGGGTTTCGGCCCGC-----------TAAACGCCTC--GTGTACAAA-AGT-AGGCGGGGAGGAG-GAGTTGGTGA-ATTCATCG-ATATCTGAGATCTTCATCTTGTTGGCGCTTGTTTGAAGC------------------------------------------TTGTGCTGAC-------------------TAGACAGGCGGAGTTGTGTAGAATTTATTGTATCTTGATGTTCTGCATTGTCGTGTTGT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
#=GC SS_cons                    ---------------------------------------------------------------------------------------------------------------------------------------------------------..................................----......(((((((((((...........((((((((((........)))))))))).........))))))))))).......-...............((.((((......))))....))................................------------------------------------------------------------------------------...................-------------------------------------------------------......................------------------------------------------------------------------------------------------------------------------.............................................................................................(((((........)))))-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.................................................................................................................--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
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