U1 snRNA

  • U1-snRNA-as-CNAG_12993-XR.001046230

  • Traces from siRNA libraries for H99 [Burke-2019], JEC21 [GSE178393] and RNA-Seq libraries [Wallace-2020] show expression of the ncRNA. Signals for specific and unspecific siRNA samples are shown.

  • The very abundant CNAG_12993 seems hard to remove with RNAseH-based methods [Telzrow-2021].

 C. neoformans 

../../_images/u1snRNA_h99_igb.png

 

  • Fits Rfam family U1 spliceosomal RNA (RF00003) with respect to conserved primary structure elements and predicted secondary structure (with highly conserved nucleotides in red).

  • The penultimate stemloop has a highly conserved base and a loop identical to that of the last stem that is essential for splicing [Sharma-2014].

  • The conserved 5’ single stranded region base-pairs to the 5’ splice site of pre-mRNA, GTRrGT in Cryptococcus [Janbon-2014].

  • The conserved single stranded section upstream the final stemloop provides the Sm-site, common to snRNAs for the association of Sm-proteins.

../../_images/U1-RF00003-rscape.svg

RF00003

 

../../_images/U1-tremellomycetes_R2R_edit.svg

U1 snRNA Tremellomycetes [1]

../../_images/U1-tremellomycetes.png

>AE017343.1:566727-566918 Cryptococcus neoformans var. neoformans JEC21 chromosome 3 sequence
ATACTTACCTTGTCGCCTCTCGATTAGTCGCCTTCACTTTGCGACCGGGAAGGTAAGGTCTTCGCCCATAG
CACGGCGACGCATGGTCCATAAGGGGAAGACCTTGCCTTGTGCTGGCTTCGGCTGGTTCAACGACTCAATA
TCTGGCTCGGTTCGGAAGTCCTTTCGAGGGCGTCCGGACTACTCTTTTTT







  • Image source:

# STOCKHOLM 1.0
#=GF RT Comparative analysis of Tremellomycetes U1 snRNA.
#=GF RW van Nues, May 2023
#=GF https://coalispr.codeberg.page/paper
#=GS U1_snRNA/4-195 DE as-CNAG_12993-XR.001046230 ncrna 3:566728:566918:1
U1_snRNA/4-195         ATACTTACCTTGT---CGCCTCTCG-ATTAGTCGCCTTCACTTTGCGACCGGGAAGGT----AAGGT---CTTC-GCCCATAGCACGGCGAC-GCATG----G-TCCATA----AGGGGAAG---ACCTT----GCCTTGTGCTGGCTTCGGCTGGTTCA-ACG-ACTCAATATCTGGCTCG-G-TTCGGAA---GTCCTTTCGAGGGC---GTCCGGACTACTCTTTTTT---------
#=GS H99/4-195 DE CP003830.1:635458-635652 Cryptococcus neoformans var. grubii H99 chromosome 11, complete sequence----
H99/4-195              ATACTTACCTTGT---CGCCTCTCG-ATTAGTCGCCTTCACTTTGCGACCGGGAAGGT----AAGGT---CTTC-GCCCATAGCACGGCGAC-GCATG----G-TCCATA----AGGGGAAG---ACCTT----GCCTTGTGCTGGCTTCGGCTGGTTCA-ACG-ACTCAATATCTGGCTCG-G-TCCGGAA---GTCCTTTCGAGGGC---GTCCGGACTATCCTTTTTT---------
#=GS R265/4-194 DE CP025759.1:889015-889208 Cryptococcus gattii VGII R265 chromosome 1, complete sequence
R265/4-194             ATACTTACCTTGT---CGCCTCTCG-ATTAGTCGCCTTCACTTTGCGACCGGGAAGGT----AAGGT---CTTC-GCCCATAGCACGGCGAC-GCATG----G-TCCATA----AGGGGAAG---ACCTT----GCCTTGTGCTGGCTTCGGCTGGTTCA-ACG-ACTCAATATCTGGCTCG-G-TTCGGAA---GTCCTTTCGAGGGC---GTCCGGACTACTCTTTTT----------
#=GS WM276/4-195 DE CP000288.1:616923-617117 Cryptococcus gattii WM276 chromosome C, complete sequence
WM276/4-195            ATACTTACCTTGT---CGCCTCTCG-ATTAGTCGCCTTCACTTTGCGACCGGGAAGGT----AAGGT---CTTC-GCCCATAGCACGGCGAC-GCATG----G-TCCATA----AGGGGAAG---ACCTT----GCCTTGTGCTGGCTTCGGCTGGTTCA-ACG-ACTCAATATCTGGCTCG-G-TTCGGAA---GTCCTTTCGAGGGC---GTCCGGACTACTCTTTTTT---------
#=GS CryWin/4-192 DE AWGH01000008.1:666722-666923 Cryptococcus wingfieldii CBS 7118 supercont1.8, whole genome shotgun sequence
CryWin/4-192           ATACTTACCTTGT---CGCCTCTCG-ATTAGCTGCCTTCACTTAGTGGCCGGGAAGGT--T--AGGT---CTTC-GCCCATAGCACGGCGAC-ACATG----G-TCCATA----GGGGGAAG---ACCT--T--GCCTTGTGCTACCTTCGGGTGGTTCA-ACG-ACTCAATATCTGGCTCG-G-TCTGGAA---GTCCTTTCGAGGGC---GTCCGGACTACTTTTT------------
#=GS CrySki/28-217 DE BCHT01000004.1:c1361567-1361320 Cryptococcus skinneri DNA, scaffold: scaffold_3, strain: JCM 9039, whole genome shotgun sequence
CrySki/28-217          ATACTTACCTTGCT--CG--GACGGATTTAGTGGCCTTCATTCTGCCACCCGTCAGGT--TTGAT-----TTCC-GCCCATAGCACAGCGACT-CAT----GG-TCTC------AGGGGGAA-----ATC-TC-GTCTTGTGCTTGCTTCGGTGGGTTCA--CGGGCTCAATATCTGGCTCG-G-TCTGGAA---GTCCTTTCGAGGGC---GTCCGGACTATATCTTATT---------
#=GS SaiPod/24-213 DE RSCD01000001.1:518001-518263 Saitozyma podzolica strain DSM 27192 scaffold_1, whole genome shotgun sequence
SaiPod/24-213          ATACTTACCTTGC-TT-G--AACGGAATTTGTGGCCTTCACTTCGCTGCCCGTTAGGT--TTGGCT-C----TC-GCCCATAGCACAGCGAC-CCGATC---G-TCTC------AGGGGA----T-AGCC-TC-GTCTTGTGCTGGCTTCGGCTGGTTCACTC--GCTCAATATCTGGCTGG-G-TCTGG-AA--GTCCTTTCGGGGGC--GG-CCGGACTATCCCTTTT----------
#=GS NaeEnc/12-200 DE MCFC01000007.1:7206-7415 Naematelia encephala strain 68-887.2 BCR39scaffold_7, whole genome shotgun sequence
NaeEnc/12-200          ATACTTACCTTGC-TT-G--AGCAGATCGTGCAGCCTTCACTCAGCTGCCTGTTAGGT--TTGGTC-T----CC-GCCCATAGCACAGCGACA-CATA---TG-TCTC------AGGGGG----C-GACC-TC-GTCTTGTGCTGGCTTCGGCTGGTTCACTC--GCTGAATATCTGGCTTG-G-TTCGGAT---GTCCCTTCGGGGGC---GTCCGGACTATCCTTTT-----------
#=GS TakKor/12-198 DE BCKT01000019.1:214288-214505 Takashimella koratensis DNA, scaffold: scaffold_18, strain: JCM 12878, whole genome shotgun sequence
TakKor/12-198          ATACTTACCTTGC-TT-G--GTCGA-ATTCGTGGCTTTCAACGCGCTGCTCGACAGGT--TTGGCC-T----CC-GCCCATAGCACGGCGACC-CAT----GG-TCCT------AGGGGG----C-GGCC-TC-GTCTTGTGCTAGCTTCGGCTGGTTCACTC--GCTCAATATCTGGCTCG-G-TCTGGAA---GTCCTTTCGGGGGC---GTCCGGACTAACCTTTT-----------
#=GS TakTep/70-257 DE BCKS01000003.1:c685170-684904 Takashimella tepidaria DNA, scaffold: scaffold_2, strain: JCM 11965, whole genome shotgun sequence
TakTep/70-257          ATACTTACCTTGC-TT-G--AACGA-ATTCGTGGCTTTCAATGCGCCACTCGTTAGAT--TTGGCT-T----CC-GCCCATAGCACAGCGACC-CAT----GG-TCTT------AGGGGG----C-GGCC-TT-ATCTTGTGCTGGCTTCGGCTGGTTCACTC--GCTCAATATCTGGCTCG-G-TCTGGAA---GTCCTCTCGGGGGC---GTCCGGACTAAACCTTTT----------
#=GS TreMes/7-196 DE AFVY01000392.1:c181797-181593 Tremella mesenterica DSM 1558 strain Fries TREMEscaffold_19_Cont392, whole genome shotgun sequence
TreMes/7-196           ATACTTACCTTGT-TT-G--AACGG-ATTAGCTGCCATCATCCTGCAGCCCGTTAGGC--TTGGCC-T----CC-GCCCATTGTACAGCGAC-CCACAC---G-TCTTC-----AGGGGG----C-GGCC-TC-GTCTTGTGCTGGCTTCGGCTGGTTCACTC--GCTCAATATCTGGATCT-G-TCTGGAA---GTCCTTCCGAGGGC---GTCCGGACTACAGCTTTT----------
#=GS KwoSha/13-196 DE NQVO01000062.1:65384-65595 Kwoniella shandongensis strain CBS 12478 scaffold00062, whole genome shotgun sequence
KwoSha/13-196          ATACTTACCTACTG--TC--TCTTGTTTGTGTCGCCCTCACACTGCGACCAAGAAGGT--TTGGCT-T----TC-GCCCATAGCACAGCGACC-CAT----GG-TCTT------AGGGGA----C-GGCC-TT-GCTTTGTGCTGGCTTCGGCTGGTTCA--GACGGCTAATATCTGGATTG-G-TCTGGAA---GTCCTTTCGAGGGC---GTCCGGACTTTTT---------------
#=GS TreYok/7-199 DE BRDC01000028.1:c683578-683380 Tremella yokohamensis NBRC 100148 DNA, KCNB35TY.28, whole genome shotgun sequence
TreYok/7-199           ATACTTACCTTGC-TT-G--GATGG-TTTAGCCGCCCTCACATTGCGGCCCATCAGGT--TTGGCCCC-----C-GCCCATTGCACGGCGAC-CCATAT---G-TCCATTTGTCAGGGG-----AGGGCC-TT-GCCTTGTGCTTGCTTCGGCGGGTTCACTC--GCTTCATCTTTGGCTGG-G-TCTGGAA---GTCCTTTCGAGGGC---GTCTGGACTTTTTACT------------
#=GS TreFuc/6-201 DE BRDD01000079.1:c4839-4639 Tremella fuciformis NBRC 9317 DNA, KCNB80TF.79, whole genome shotgun sequence
TreFuc/6-201           ATACTTACCTTGC-TT-G--GATGG-TTTAGCCGCCCTCACACTGCGGCCCATCAGGT--TTGGCCCC-----C-GCCCATTGCACGGCGAC-CCATAT---G-TCCATTTACCAGGGG-----AGGGCC-TT-GTCTTGTGCTTGCTTCGGCGGGTTCACTC--GCTTCATATTTGGCTGG-G-TCTGGAA---GTCCTTTCGAGGGC---GTCTGGACTTTTTCCTTTT---------
#=GS JVisVic/12-209 DE ADPYG010000088.1:c124102-123890 Vishniacozyma victoriae isolate T18_1_22C Contig_88, whole genome shotgun sequence
JVisVic/12-209         ATACTTACCTTGC-TT-G--GATGG-TTTAGCTCTCTTCACACTAGAGCCCATCAGGT--TTGAT-----CTCC-GCCCATTGCACAGCGACA-CAA----TGGTTCTTC----AGGGGGAG-----ATC-TT-ATCTTGTGCTTCCTTCGGGGGGTTCACTC--GCTCAATAATTGGCTCT-G-TCCGGAA---GTCCTTTCGAGGGC---GTCTGGACTACAAAAACAAATTCTT---
#=GS KwoHev/13-199 DE ASQC01000005.1:c77241-77009 Kwoniella heveanensis CBS 569 cont2.5, whole genome shotgun sequence
KwoHev/13-199          ATACTTACCTTCAC--TG--TTTAG-GAGTGCGGCCTTCACTATGCTGCCTGAAACG--TCAGA------CCTTCGCTCATAGCACGGCGACC-CAC----GG-TCCCA-----AGGGAAGG------TCTTT--CGTTGTGCTGGCTTCGGCTGGTTCA--CGGTGTAAATATTTCGATCT-G-GCTGGAA---GTCCTTTCGAGGGC---GTCCGGCCTACCTTATT-----------
#=GS DioHun/11-209 DE JAMRJJ010000001.1:c3248997-3248779 Dioszegia hungarica strain Y1 Contig1, whole genome shotgun sequence
DioHun/11-209          ATACTTACCTTGC-TT-G--AACCG-TTTAGGCTCCTTCATTCTGAGTCCGGTTAGGT--CTGGTC-T----CC-GCCCATAGCACAGCGAC-CCATTC---G-TCTC------AGGGGG----C-GGCC-TC-ATCTTGTGCTCGCTTCGGCGGGTTCACTC--GCTCAATATCTGGCTCG-G-TCCGG-AA--GTCCTTTCGAGGGC--GG-CTGGACCATATCAAAATTATCCTTTT
#=GS DioAur/9-208 DE BCKN01000001.1:741400-741609 Dioszegia aurantiaca DNA, scaffold: scaffold_0, strain: JCM 2956, whole genome shotgun sequence
DioAur/9-208           ATACTTACCTTGC-TT-G--AACCGATTTTGACTCCTTCAACCTGAGTCCGGTTAGGT--CTGGTC-T----CC-GCCCATAGCACAGCGAC-CCATAC---G-TCTC------AGGGGG----C-GGCC-TC-ATCTTGTGCTCGCTTCGGCGGGTTCACTC--GCCCAATATCTGGCTCG-G-TCCGG-AG--GTCCTTTCGAGGGC--AG-CTGGGCCATCATACACATTCTCTTTT
#=GS PapLau/4-192 DE JDSR01000623.1:c17688-17487 Papiliotrema laurentii RY1 contig_644, whole genome shotgun sequence
PapLau/4-192           ATACTTACCTTGC-TT-G--AACGG-CATTGCGGCCCTCAATCTGCCGCCCGTTAGGT--TTGGTC-T----CC-GCCCATTGCACAGCGAC-CCATAT---G-TCTC------AGGGGG----C-GACC-TC-GTCTTGTGCTGGCTTCGGCTGGTTCACTC--GCTCAATATCTGGCTCT-G-TCCGGCG---GTCCCTTCGGGGGC---GGCTGGACTACTCTTATT----------
#=GS BulAlb/4-194 DE CAMYTR010000005.1:12103-12326 Bullera alba genome assembly, contig: jcf7180000012097, whole genome shotgun sequence
BulAlb/4-194           ATACTTACCTTGC-TT-G--AACGGTTTGTGCCGCCTTCACTCTGTGGCCCGTTAGGT--TTGGTT-T----CC-GCCCATAGCACAGCGACC-CATTTATGGCTC--------AGGGGG----C-GACC-TC-GTCTTGTGCTGGCTTCGGCTGGTTCACTC--GCTTAATATCTGGCTCG-G-TCCGGCG---GTCCCTTCGGGGGC---GGCTGGACTATCTTATT-----------
#=GS DioCro/71-267 DE BCKK01000001.1:1239755-1240025 Dioszegia crocea DNA, scaffold: scaffold_0, strain: JCM 2961, whole genome shotgun sequence
DioCro/71-267          ATACTTACCTTGC-TT-G--AACCG-TTTTGACTCCTTCACCCTGAGTCCGGTTAGGT--CTGGTC-T----CC-GCCCATAGCACAGCGAC-CCATAC---G-TCTC------AGGGGG----C-GGCC-TA-ATCTTGTGCTCGCTTCGGCGGGTTCACTC--GCCCAATATCTGGCTCG-G-TCCGG-GG--GTCCTTTCGAGGGC--AA-CTGGGCCATTATATATAAACTTCT--
#=GS TriPor/4-190 DE BCJG01000001.1:c1746683-1746490 Trichosporon porosum DNA, scaffold: scaffold_0, strain: JCM 1458, whole genome shotgun sequence
TriPor/4-190           ATACTTACCTTGC-TT-G--AACCG-ATCAGTAGCCCTCACCTTGCTACCGGTTAGGC--TTG----T-TCCTT-GCCCATTGCACAGCGACT-TAT----AG-TCTC------AGGGAAGGA-C----C-TC-GTCTTGTGCTGGCTTCGGCTGGTTCACTC--GCTTCATATTTGGCTGA-G--CTAGT---TGTCCTCTCGGGGGCA---GCTGG-CACTACTCTTTT---------
#=GS CryFla/4-186 DE CAUG01000242.1:c39311-39109 Cryptococcus flavescens NRRL Y-50378 WGS project CAUG00000000 data, contig NODE_338_length_195656_cov_46_022861, whole genome shotgun sequence
CryFla/4-186           ATACTTACCTTGC-TT-G--AACGG-CTTAGCGGCCTTCACTCTGCCGCCCGTTAGAT--TTGGAT-T----CC-GCCCATAGCACAGCGAC-CCATAC---G-TCTC------AGGGGG----C-GTCC-TT-GTCTTGTGCTGGCTTCGGCTGGTTCACTC--GCTCAATATCTGGCTCG-G-CTTGAC---GGTCCCTTCGGGGGTC---GTTGGGCTTTT----------------
#=GS PapTer/4-186 DE JAHXHD010000884.1:c17061-16865 Papiliotrema terrestris strain LS28 scaffold-883, whole genome shotgun sequence
PapTer/4-186           ATACTTACCTTGC-TT-G--AACGG-CTTAGCGGCCTTCACTCTGCCGCCCGTTAGAT--TTGGAT-T----CC-GCCCATAGCACAGCGAC-CCATAT---G-TCTC------AGGGGG----C-GTCC-TT-GTCTTGTGCTGGCTTCGGCTGGTTCACTC--GCTCAATATCTGGCTCG-G-CTCGAC---GGTCCCTTCGGGGGTC---GTTGGGCTTTT----------------
#=GS TriCor/22-204 DE JXYL01000012.1:c489969-489760 Trichosporon coremiiforme strain JCM 2938 scaffold_0012, whole genome shotgun sequence
TriCor/22-204          ATACTTACCTTGT-TT-G--GACGG---ATGTGGCCCTCAGACTGCTGCCCGTCAGGT----CATTAG---CAC-GCCCATTGCACAGCGACT-CAC----AG-TCTC------AGGGGTG--AG-AATG----GCCTTGTGCTGGCTTCGGCTGGTTCACTC--GCTCAATATTTGGCTCT-G-CCCAGC----ATCCTCTCGGGGGT----GCCGGGCTACCATTTT-----------
#=GS TriOvo/13-196 DE JAMFRG010000021.1:c297411-297210 Trichosporon ovoides strain Y9002B ctg_21, whole genome shotgun sequence
TriOvo/13-196          ATACTTACCTTGT-TT-G--GACGG----TGGGGCCCTCAAACTGCTCTCCGTCAGGC----CGTG-GA--CAC-GCCCATTGCACAGCGACT-CAC----AG-TTCTC-----AGGGGTG--GA-CGCG----GCCTTGTGCTGGCTTCGGCTGGTTCACTC--GCTCAATATTTGGCTCT-G-CCCGGC----GTCCTCTCGGGGGT----GCTGGGCTACGATTTTT----------
#=GS TriFae/13-193 DE JXYK01000004.1:c80138-79940 Trichosporon faecale strain JCM 2941 scaffold_0004, whole genome shotgun sequence
TriFae/13-193          ATACTTACCTTGT-TT-G--GACGG----CGCGGTCCTCAGATTGCTGCCCGTCAGG---C-CATTTG---CAC-GCCCATTGCACAGCGACT-CAC----AG-TCTC------AGGGGTG---GGAATG-A---CCTTGTGCTGGCTTCGGCTGGTTCACTC--GCTCAATATTTGGCTCT-G-CCCGGC----GTCCTCTCGGGGGT----GCTGGGCTACCTTTT------------
#=GS VanHum/21-209 DE QKWK01000010.1:c388543-388320 Vanrija humicola strain CBS 4282 CBS4282_scaffold10, whole genome shotgun sequence
VanHum/21-209          ATACTTACCTTGC-TT-G--AACTG-TTTACCGCTCCTCACTCTGGCGGCAGTTAGGC--TTGGGG-----CTC-GCCCATTGCACAGCGACT-CAT----AG-TCTT------AGGGGAG---G-TCCT-C--GTCTTGTGCTGGCTTCGGCTGGTTCACTC--GCTCAATATCTGGCTCG-G-TCTGG-GC--GTCCTCTCGGGGGC--AG-CCAGACTACATCTTATT---------
#=GS NaeAur/12-200 DE JAKFAO010000010.1:c323656-323427 Naematelia aurantialba strain NX-20 Contig10, whole genome shotgun sequence
NaeAur/12-200          ATACTTACCTTGC-TT-G--AACGGTTTGTGCGGCCTTCACCCTGCTGCCCGTTAGGT--TTGGT-----CTCC-GCCCATAGCACAGCGAC-ACATAC---G-TCTC------AGGGGGCGA-C---CT-C--GTCTTGTGCTGGCTTCGGCTGGTTCACTC--GCTAAATATCTGGCTCG-G-TTCGGG---TGTCCCTTCGGGGGCG---TCCGGACTATCCTTTT-----------
#=GS KwoPin/13-205 DE ASCL01000010.1:679938-680242 Kwoniella pini CBS 10737 cont1.10, whole genome shotgun sequence
KwoPin/13-205          ATACTTACCTTATG--TA--CTCGGACTGTTCCGCCTTCACGATGCGGACCGGGATGA--T-AGTG----TCTC-GCTCATAGCACGGCGACC-CAT----GG-TCCATA----AAGGGAGA----CGCT-T--TCGTTGTGCTGGCTTCGGCTGGTTCA--TACGTTAAATATTTCGATCT-GTCCAGGTA---GTCCTTTCGAGGGC---GACCTGGCTACACCTTTTT---------
#=GS KwoBes/9-210 DE ASCK01000010.1:502008-502300 Kwoniella bestiolae CBS 10118 cont1.10, whole genome shotgun sequence
KwoBes/9-210           ATACTTACCTTGTA--TC--GGGATTTCCTACCGCCTTCAGCCTGCGGTGTCCCAGG---TCGGGCTT----CC-GCCCATAGCACGGCGAC-GCATG----G-TCCATA----AGGGGG----CAGCCC-TT--CCTTGTGCTGGCTTCGGCTGGTTCA--GATGCTCAATATTTAGATCT-GTCCGGGTA---GTCCTTTCGAGGGC---GACCTGGCTACCACCATAATTCCTTTTT
#=GS KwoMan/19-220 DE ASQF01000028.1:674064-674296 Kwoniella mangroviensis CBS 8886 cont1.28, whole genome shotgun sequence
KwoMan/19-220          ATACTTACCTTGTA--TC--GGGATTTTCTACCGCCTTCAGCCTGCGGTGTCCCAGG---TCGGGCTT----CC-GCCCATAGCACGGCGAC-GCATG----G-TCCATA----AGGGGG----CAGCCC-TT--CCTTGTGCTGGCTTCGGCTGGTTCA--GATGCTCAATATTTAGATGT-GTCCGGGTA---GTCCTTTCGAGGGC---GACCTGGCTACCCAAAATTCATTCTTTT
#=GS KwoDej/11-202 DE ASCJ01000036.1:523616-523823 Kwoniella dejecticola CBS 10117 cont1.36, whole genome shotgun sequence
KwoDej/11-202          ATACTTACCTAGTT--AT--CCTGAGGCGTGCTCCCTTCACTTTGGAGCTCAGGAGGA--T-GTCT-T---CAC-GCTCATAGCACGGCGACC-CAT----GG-TCCATC----AAGGGTG---C-GGAC-A--TCTTTGTGCTGGCTTCGGCTGGTTCA--ATGGCCTAATATTTCGATCT-GTCCAGGTA---GTCCTTTCGAGGGC---GACCTGGCTACACTTTTT----------
#=GS CutDas/4-187 DE BEDX01000007.1:216811-217003 Cutaneotrichosporon daszewskae DNA, scaffold: scaffold_7, strain: JCM_11166, whole genome shotgun sequence
CutDas/4-187           ATACTTACCTTGA-CT-G--CCCTG-TTTACGTGCCCTCATTCTGCGCGCAGGGAGGC--TTGGG-----CCCC-GCCCATTGCACGGCGACT-TAT----AG-TCCT------AGGGGAGG-----CCC-TC-GCCTTGTGCTGGCTTCGGCTGGTTCACTC--TCTCAATATTTGGCTA--G-GTCG--G-CCGTCCTCTCGGGGGCGG----TGGCCGTCTTTTT------------
#=GS CutCut/4-186 DE LTAL01000518.1:84533-84735 Cutaneotrichosporon cutaneum strain ACCC 20271 contig518, whole genome shotgun sequence
CutCut/4-186           ATACTTACCTTGT-CT-G--ACGCA-ATGCCGCGCCCTCACTTTGCGCGTGCGTAGGT----CAGT---TCCAC-GCCCATTGCACAGCGACT-TAT----AG-TCTT------AGGGGTGGA---GCTG----GTCTTGTGCTGCTTTCGAGTGGTTCACAG--GCCCAATATTTAGATGGAG-TCTCG-----GTCTCTTCGGAGGT---C-CGGGACACTTTTT-------------
#=GS CutOle/7-192 DE QKWL01000004.1:c1553947-1553745 Cutaneotrichosporon oleaginosum strain ATCC 20508 ATCC20508_contig04, whole genome shotgun sequence
CutOle/7-192           ATACTTACCTTGC-TT-G--CTCGG-TTAAATGGCCCTCACCCTGCCATCCGAGAGGC--TTGCT-----CCTC-GACCATTGCACGGCGACT-CAC----AG-TCCT------AGTGGAGG-----GGC-TT-GCCTTGTGCTGGCTTCGGCTGGTTCACTC--GTTCAATATTTGGCTCT-G-CCTGT-CT---CCCCTTCGGGGG---TA-GCGGGCTACCATTTTT----------
#=GS CutMuc/7-192 DE BCJT01000005.1:1668698-1668898 Cutaneotrichosporon mucoides DNA, scaffold: scaffold_4, strain: JCM 9939, whole genome shotgun sequence
CutMuc/7-192           ATACTTACCTTGT-TT-G--CTCGG-TTTCATGGCCCTCATCCTGCCATCCGAGAGGT--TTGCT-----CCTC-GACCATTGCACAGCGACT-CAT----AG-TCTTC------GTGGAGG-----GGC-CT-GCCTTGTGCTGGCTTCGGCTGGTTCACTC--GCTCAATATTTGGCTCT-G-CCTGT-CT---CCCCTTCGGGGG---TA-GCGGGCTACCATTTTT----------
#=GS PasPL2/4-191 DE JAMFRE010000121.1:12701-12898 Pascua sp. PL2904B ctg_121, whole genome shotgun sequence
PasPL2/4-191           ATACTTACCTTGC-TT-G--AGCCG-TTTAGCCTCCCTCACTCTGGGGCCGGTTACGGA-T-TGG--G---CTC-GCCCATTGCACGGCGACT-CAT----AG-TCCT------AGGGGAG---A--CCA-T-TCCGTTGTGCTTGCTTACGCAGGTTCACTC--GCTCAATATTTGGCGCC-G-CCTTCC---TATCCTCTCGGGGATA---GGGGGGCAACACTTTTT----------
#=GC SS_cons           ...........<<<..<<..(((((.....(((((.........))))))))))(((((...(((((..(((((..((...........((((........)).)).........)).)))))..)))))...)))))((.((((((....)))))).))..>>>>>................(.((((((..(((((((....)))))))..)))))))....................
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Notes